| 1. Round | 16/08/2021 | West Ham United U23 | - | Arsenal FC U23 | 6:1 | ||||
| 2. Round | 20/08/2021 | Arsenal FC U23 | - | Crystal Palace U23 | 4:2 | ||||
| 3. Round | 27/08/2021 | Tottenham Hotspur U23 | - | Arsenal FC U23 | 1:2 | ||||
| 4. Round | 11/09/2021 | Arsenal FC U23 | - | Manchester United U23 | 3:1 | ||||
| 5. Round | 19/09/2021 | Chelsea FC U23 | - | Arsenal FC U23 | 1:6 | ||||
| 6. Round | 25/09/2021 | Manchester City U23 | - | Arsenal FC U23 | 2:2 | ||||
| 7. Round | 01/10/2021 | Arsenal FC U23 | - | Brighton & Hove Albion U23 | 3:0 | ||||
| 8. Round | 16/10/2021 | Liverpool FC U23 | - | Arsenal FC U23 | 3:0 | ||||
| 9. Round | 22/10/2021 | Arsenal FC U23 | - | Everton FC U23 | 4:0 | ||||
| 10. Round | 29/10/2021 | Leeds United U23 | - | Arsenal FC U23 | 2:4 | ||||
| 11. Round | 06/11/2021 | Arsenal FC U23 | - | Leicester City U23 | 3:3 | ||||
| 24. Round | 04/04/2022 | Arsenal FC U23 | - | Manchester City U23 | 3:3 |
England
Jamaica