| 6. Round | 14/01/2023 | Willem II [U21] | - | Vitesse [U21] | 2:3 |  |
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| 7. Round | 21/01/2023 | NEC Nijmegen [U21] | - | Willem II [U21] | 6:3 | ||||
| 1. Round | 28/01/2023 | Willem II [U21] | - | SC Cambuur [U21] | 1:5 | ||||
| 2. Round | 03/02/2023 | FC Emmen [U21] | - | Willem II [U21] | 2:2 | |
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| 3. Round | 11/02/2023 | sc Heerenveen [U21] | - | Willem II [U21] | 1:3 | |
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| 4. Round | 18/02/2023 | Willem II [U21] | - | Go Ahead Eagles [U21] | 1:1 | ||||
| 5. Round | 11/03/2023 | Roda JC Kerkrade [U21] | - | Willem II [U21] | 4:1 | |
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| 9. Round | 18/03/2023 | Willem II [U21] | - | FC Emmen [U21] | 0:0 |  |
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| 8. Round | 31/03/2023 | SC Cambuur [U21] | - | Willem II [U21] | 3:3 | |
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| 11. Round | 15/04/2023 | Go Ahead Eagles [U21] | - | Willem II [U21] | 4:1 | ||||
| 10. Round | 22/04/2023 | Willem II [U21] | - | sc Heerenveen [U21] | 1:0 | ||||
| 12. Round | 06/05/2023 | Willem II [U21] | - | Roda JC Kerkrade [U21] | 0:0 | ||||
| 13. Round | 13/05/2023 | Vitesse [U21] | - | Willem II [U21] | 1:1 | ||||
| 14. Round | 20/05/2023 | Willem II [U21] | - | NEC Nijmegen [U21] | 2:3 |
Netherlands