| Primera División | Matches | W | D | L |  |
 |
 |
| home | 4 | 3 | - | 1 | 15 | 2 | 2 |
| away | 5 | 2 | 3 | - | 17 | - | - |
| overall | 9 | 5 | 3 | 1 | 32 | 2 | 2 |
| Segunda División | Matches | W | D | L | |
|
|
| home | - | - | - | - | - | - | - |
| away | 1 | - | - | 1 | 5 | - | - |
| overall | 1 | - | - | 1 | 5 | - | - |
| Primera División | Home | - | Guest | |
|
|
Results |
| 21/03/22 | Boston River | - | Defensor Sporting | 3 | - | - | 1:1 |
| 15/07/23 | Defensor Sporting | - | Danubio | 3 | - | - | 2:1 |
| 30/07/23 | Defensor Sporting | - | Liverpool | 3 | 1 | - | 0:1 |
| 15/11/23 | CA Cerro | - | Defensor Sporting | 5 | - | - | 1:1 |
| 14/04/24 | Defensor Sporting | - | River Plate | 5 | 1 | 2 | 2:1 |
| 12/05/24 | Progreso | - | Defensor Sporting | 4 | - | - | 1:4 |
| 09/06/24 | Deportivo Maldonado | - | Defensor Sporting | 1 | - | - | 0:2 |
| 07/09/24 | CA Cerro | - | Defensor Sporting | 4 | - | - | 1:1 |
| 14/11/24 | Defensor Sporting | - | Progreso | 4 | - | - | 3:0 |
| Segunda División | Home | - | Guest | |
|
|
Results |
| 05/10/21 | Central Español | - | Defensor Sporting | 5 | - | - | 1:0 |
Uruguay