| Primera División | Matches | W | D | L |  |
 |
 |
| home | 5 | 1 | 2 | 2 | 7 | - | - |
| away | 3 | 1 | 1 | 1 | 3 | - | 2 |
| overall | 8 | 2 | 3 | 3 | 10 | - | 2 |
| Primera División | Home | - | Guest | |
|
|
Results |
| 05/03/21 | River Plate | - | Guaireña FC | 1 | - | 2 | 0:1 |
| 28/11/21 | Guaireña FC | - | Guaraní | 1 | - | - | 1:1 |
| 12/02/22 | Guaireña FC | - | Club Olimpia | 1 | - | - | 1:3 |
| 14/03/22 | Guaireña FC | - | 12 de Octubre de Itauguá | 2 | - | - | 0:0 |
| 12/06/22 | Guaireña FC | - | General Caballero DJLM | 2 | - | - | 1:2 |
| 16/07/22 | Tacuary | - | Guaireña FC | - | - | - | 0:0 |
| 23/09/22 | Sportivo Ameliano | - | Guaireña FC | 2 | - | - | 2:0 |
| 10/10/22 | Guaireña FC | - | Resistencia SC | 1 | - | - | 3:2 |
Paraguay