| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 3 | 2 | 1 | - | 3 | - | - |
| away | 2 | - | - | 2 | 5 | - | - |
| overall | 5 | 2 | 1 | 2 | 8 | - | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | - | - | 1 | 2 | - | 1 |
| away | 2 | 1 | 1 | - | 2 | - | - |
| overall | 3 | 1 | 1 | 1 | 4 | - | 1 |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 15/03/18 | The Strongest | - | Peñarol | 3 | - | - | 1:0 |
| 27/04/18 | Peñarol | - | Libertad | 2 | - | - | 2:0 |
| 05/05/22 | Club Olimpia | - | Peñarol | 2 | - | - | 1:0 |
| 26/05/22 | Peñarol | - | Colón de Santa Fe | - | - | - | 2:1 |
| 30/05/25 | Peñarol | - | Vélez Sarsfield | 1 | - | - | 0:0 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 23/05/19 | Deportivo Cali | - | Peñarol | 2 | - | - | 1:1 |
| 23/07/21 | Peñarol | - | Nacional | 2 | - | 1 | 0:1 |
| 08/03/23 | River Plate | - | Peñarol | - | - | - | 0:4 |
Brazil