| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | - | - | - | - | - | - | - |
| away | 1 | 1 | - | - | 2 | 1 | - |
| overall | 1 | 1 | - | - | 2 | 1 | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | - | - | - | - | - | - | - |
| away | 1 | - | 1 | - | 3 | - | - |
| overall | 1 | - | 1 | - | 3 | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 29/04/21 | Santa Fe | - | Fluminense RJ | 2 | 1 | - | 1:2 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 20/05/22 | Unión de Santa Fe | - | Fluminense RJ | 3 | - | - | 0:0 |
Uruguay