| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 1 | 1 | - | - | 1 | 1 | - |
| away | 3 | 1 | - | 2 | 5 | 1 | - |
| overall | 4 | 2 | - | 2 | 6 | 2 | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 14/05/15 | Cruzeiro | - | São Paulo FC | 1 | - | - | 4:3 pso |
| 14/04/16 | São Paulo FC | - | River Plate | 1 | 1 | - | 2:1 |
| 19/05/16 | Atlético Mineiro | - | São Paulo FC | 3 | - | - | 2:1 |
| 21/04/21 | Sporting Cristal | - | São Paulo FC | 1 | 1 | - | 0:3 |
Uruguay