| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 1 | - | 1 | - | 3 | - | - |
| away | 2 | - | - | 2 | 5 | - | - |
| overall | 3 | - | 1 | 2 | 8 | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 20/05/22 | River Plate | - | Colo-Colo | 1 | - | - | 4:0 |
| 01/03/24 | Colo-Colo | - | Godoy Cruz | 3 | - | - | 0:0 |
| 25/09/24 | River Plate | - | Colo-Colo | 4 | - | - | 1:0 |
Uruguay