| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 3 | 2 | 1 | - | 8 | - | - |
| away | 2 | - | - | 2 | 6 | - | - |
| overall | 5 | 2 | 1 | 2 | 14 | - | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | 1 | - | - | 5 | - | - |
| away | - | - | - | - | - | - | - |
| overall | 1 | 1 | - | - | 5 | - | - |
| Copa Mercosur | Matches | W | D | L | |
|
|
| home | 2 | 1 | - | 1 | 7 | - | 1 |
| away | - | - | - | - | - | - | - |
| overall | 2 | 1 | - | 1 | 7 | - | 1 |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 03/03/04 | Boca Juniors | - | Colo-Colo | 2 | - | - | 2:0 |
| 26/03/04 | Colo-Colo | - | Bolívar | 1 | - | - | 2:0 |
| 28/03/08 | Boca Juniors | - | Colo-Colo | 4 | - | - | 4:3 |
| 13/03/09 | Colo-Colo | - | LDU Quito | 2 | - | - | 3:0 |
| 17/03/10 | Colo-Colo | - | Vélez Sarsfield | 5 | - | - | 1:1 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 26/08/10 | Colo-Colo | - | Universitario de Sucre | 5 | - | - | 3:1 |
| Copa Mercosur | Home | - | Guest | |
|
|
Results |
| 31/08/00 | Colo-Colo | - | Rosario Central | 3 | - | - | 0:1 |
| 23/08/01 | Colo-Colo | - | Independiente | 4 | - | 1 | 2:1 |
Paraguay