| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 5 | 2 | 2 | 1 | 12 | - | - |
| away | - | - | - | - | - | - | - |
| overall | 5 | 2 | 2 | 1 | 12 | - | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | 1 | - | - | 1 | - | - |
| away | - | - | - | - | - | - | - |
| overall | 1 | 1 | - | - | 1 | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 18/02/03 | Peñarol | - | Grêmio Porto Alegre | 4 | - | - | 2:2 |
| 16/03/04 | Peñarol | - | The Strongest | 1 | - | - | 4:0 |
| 27/05/11 | Peñarol | - | Vélez Sarsfield | 2 | - | - | 1:0 |
| 16/06/11 | Peñarol | - | Santos FC | 3 | - | - | 0:0 |
| 21/02/12 | Peñarol | - | Atlético Nacional | 2 | - | - | 0:4 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 20/10/10 | Peñarol | - | Goiás - GO | 1 | - | - | 3:2 |
Paraguay