| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 4 | 2 | 2 | - | 8 | - | - |
| away | 4 | 1 | 1 | 2 | 7 | 1 | 1 |
| overall | 8 | 3 | 3 | 2 | 15 | 1 | 1 |
| Recopa Sudamericana | Matches | W | D | L | |
|
|
| home | - | - | - | - | - | - | - |
| away | 1 | - | - | 1 | 4 | - | - |
| overall | 1 | - | - | 1 | 4 | - | - |
| Copa Mercosur | Matches | W | D | L | |
|
|
| home | 1 | 1 | - | - | 5 | - | - |
| away | - | - | - | - | - | - | - |
| overall | 1 | 1 | - | - | 5 | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 07/05/04 | Rosario Central | - | São Paulo FC | - | - | 1 | 1:0 |
| 10/06/04 | São Paulo FC | - | Once Caldas | 1 | - | - | 0:0 |
| 22/04/05 | Universidad de Chile | - | São Paulo FC | 1 | - | - | 1:1 |
| 26/04/07 | São Paulo FC | - | Audax Italiano | 4 | - | - | 2:2 |
| 22/05/08 | Fluminense RJ | - | São Paulo FC | 1 | 1 | - | 3:1 |
| 19/03/09 | Defensor Sporting | - | São Paulo FC | 5 | - | - | 0:1 |
| 06/08/10 | São Paulo FC | - | Internacional | 1 | - | - | 2:1 |
| 07/05/15 | São Paulo FC | - | Cruzeiro | 2 | - | - | 1:0 |
| Recopa Sudamericana | Home | - | Guest | |
|
|
Results |
| 08/09/06 | Boca Juniors | - | São Paulo FC | 4 | - | - | 2:1 |
| Copa Mercosur | Home | - | Guest | |
|
|
Results |
| 23/08/00 | São Paulo FC | - | Rosario Central | 5 | - | - | 1:0 |
Paraguay