| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 1 | 1 | - | - | 1 | - | - |
| away | 1 | 1 | - | - | 2 | - | - |
| overall | 2 | 2 | - | - | 3 | - | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | 1 | - | - | 4 | - | - |
| away | - | - | - | - | - | - | - |
| overall | 1 | 1 | - | - | 4 | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 07/03/13 | Cerro Porteño | - | Santa Fe | 2 | - | - | 1:2 |
| 13/05/15 | Santa Fe | - | Estudiantes | 1 | - | - | 2:0 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 21/10/10 | Santa Fe | - | Atlético Mineiro | 4 | - | - | 1:0 |
Ecuador