| CONCACAF Champions Cup | Matches | W | D | L |  |
 |
 |
| home | 1 | 1 | - | - | 3 | - | - |
| away | 1 | - | - | 1 | 1 | - | - |
| overall | 2 | 1 | - | 1 | 4 | - | - |
| North American SuperLiga | Matches | W | D | L | |
|
|
| home | - | - | - | - | - | - | - |
| away | 2 | - | - | 2 | 5 | - | - |
| overall | 2 | - | - | 2 | 5 | - | - |
| CONCACAF Champions Cup | Home | - | Guest | |
|
|
Results |
| 22/09/10 | Columbus Crew | - | Santos Laguna | 1 | - | - | 1:0 |
| 20/10/11 | Santos Laguna | - | Colorado Rapids | 3 | - | - | 2:0 |
| North American SuperLiga | Home | - | Guest | |
|
|
Results |
| 17/07/08 | CD Chivas | - | Santos Laguna | 2 | - | - | 1:0 |
| 22/06/09 | New England Revolution | - | Santos Laguna | 3 | - | - | 4:2 |
Jamaica