| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 1 | - | 1 | - | 2 | - | - |
| away | 2 | 1 | - | 1 | 3 | - | 1 |
| overall | 3 | 1 | 1 | 1 | 5 | - | 1 |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 27/02/14 | Atlético Mineiro | - | Santa Fe | 2 | - | 1 | 2:1 |
| 01/02/18 | Deportivo Táchira | - | Santa Fe | 1 | - | - | 2:3 |
| 26/04/18 | Santa Fe | - | Flamengo RJ | 2 | - | - | 0:0 |
Uruguay