| Primera División | Matches | W | D | L |  |
 |
 |
| home | 7 | 1 | 6 | - | 14 | - | - |
| away | 2 | - | - | 2 | 3 | - | - |
| overall | 9 | 1 | 6 | 2 | 17 | - | - |
| Primera División | Home | - | Guest | |
|
|
Results |
| 21/11/04 | Cruz Azul | - | Santos Laguna | 1 | - | - | 1:0 |
| 28/08/05 | Santos Laguna | - | Deportivo Guadalajara | 1 | - | - | 3:0 |
| 16/03/06 | Cruz Azul | - | Santos Laguna | 2 | - | - | 4:1 |
| 06/08/06 | Santos Laguna | - | CF Monterrey | 1 | - | - | 2:2 |
| 01/10/06 | Santos Laguna | - | Atlas Guadalajara | 2 | - | - | 1:1 |
| 11/05/07 | Santos Laguna | - | CF Pachuca | 3 | - | - | 1:1 |
| 04/08/08 | Santos Laguna | - | Pumas UNAM | 2 | - | - | 1:1 |
| 14/09/08 | Santos Laguna | - | Club Necaxa | 1 | - | - | 1:1 |
| 08/03/09 | Santos Laguna | - | Cruz Azul | 4 | - | - | 2:2 |
Mexico