| Copa Sudamericana | Matches | W | D | L |  |
 |
 |
| home | 2 | 1 | - | 1 | 5 | - | 1 |
| away | - | - | - | - | - | - | - |
| overall | 2 | 1 | - | 1 | 5 | - | 1 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 03/08/18 | São Paulo FC | - | Colón de Santa Fe | 2 | - | 1 | 0:1 |
| 09/06/23 | São Paulo FC | - | Deportes Tolima | 3 | - | - | 5:0 |
Uruguay