| Primera División | Matches | W | D | L |  |
 |
 |
| home | 4 | 3 | - | 1 | 7 | - | - |
| away | 4 | - | 2 | 2 | 15 | 1 | 2 |
| overall | 8 | 3 | 2 | 3 | 22 | 1 | 2 |
| Primera División | Home | - | Guest | |
|
|
Results |
| 14/08/05 | Santos Laguna | - | UANL Tigres | 2 | - | - | 1:4 |
| 16/08/09 | Santos Laguna | - | Cruz Azul | 2 | - | - | 3:2 |
| 11/04/10 | Pumas UNAM | - | Santos Laguna | 6 | - | - | 1:0 |
| 14/08/11 | Pumas UNAM | - | Santos Laguna | 3 | - | 1 | 1:1 |
| 12/01/14 | Cruz Azul | - | Santos Laguna | 4 | - | 1 | 2:1 |
| 31/08/14 | Atlas Guadalajara | - | Santos Laguna | 2 | 1 | - | 1:1 |
| 29/08/16 | Santos Laguna | - | Club León | 3 | - | - | 1:0 |
| 07/11/16 | Santos Laguna | - | Chiapas FC | - | - | - | 2:0 |
Mexico