| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 2 | - | - | 2 | 6 | - | - |
| away | 1 | 1 | - | - | 1 | - | - |
| overall | 3 | 1 | - | 2 | 7 | - | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | 1 | - | - | - | - | - |
| away | - | - | - | - | - | - | - |
| overall | 1 | 1 | - | - | - | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 09/05/14 | Atlético Nacional | - | Defensor Sporting | 1 | - | - | 0:2 |
| 16/05/18 | Defensor Sporting | - | Cerro Porteño | 5 | - | - | 0:1 |
| 21/02/19 | Defensor Sporting | - | Atlético Mineiro | 1 | - | - | 0:2 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 04/08/10 | Defensor Sporting | - | Club Olimpia | - | - | - | 2:0 |
Argentina