| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 2 | 1 | - | 1 | 5 | - | - |
| away | 2 | - | - | 2 | 10 | 1 | 2 |
| overall | 4 | 1 | - | 3 | 15 | 1 | 2 |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | - | - | - | - | - | - | - |
| away | 1 | - | 1 | - | 5 | - | - |
| overall | 1 | - | 1 | - | 5 | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 24/01/06 | Colo-Colo | - | Deportivo Guadalajara | 3 | - | - | 1:3 |
| 04/04/07 | Colo-Colo | - | LDU Quito | 2 | - | - | 4:0 |
| 25/03/10 | Vélez Sarsfield | - | Colo-Colo | 5 | 1 | - | 2:1 |
| 07/04/11 | Santos FC | - | Colo-Colo | 5 | - | 2 | 3:2 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 30/11/06 | CF Pachuca | - | Colo-Colo | 5 | - | - | 1:1 |
Uruguay