| Copa Sudamericana | Matches | W | D | L |  |
 |
 |
| home | - | - | - | - | - | - | - |
| away | 2 | 1 | 1 | - | 2 | 1 | - |
| overall | 2 | 1 | 1 | - | 2 | 1 | - |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 12/05/17 | São Paulo FC | - | Defensa y Justicia | 1 | 1 | - | 1:1 |
| 09/03/18 | América de Cali | - | Defensa y Justicia | 1 | - | - | 0:3 |
Paraguay