| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 9 | 5 | 2 | 2 | 24 | - | 1 |
| away | 1 | - | - | 1 | 5 | - | - |
| overall | 10 | 5 | 2 | 3 | 29 | - | 1 |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | 1 | - | - | 2 | - | 1 |
| away | - | - | - | - | - | - | - |
| overall | 1 | 1 | - | - | 2 | - | 1 |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 02/06/11 | Cerro Porteño | - | Santos FC | 2 | - | - | 3:3 |
| 11/04/19 | Cerro Porteño | - | Atlético Mineiro | 2 | - | - | 4:1 |
| 01/08/19 | Cerro Porteño | - | San Lorenzo | 2 | - | - | 2:1 |
| 04/08/21 | Fluminense RJ | - | Cerro Porteño | 5 | - | - | 1:0 |
| 28/04/22 | Cerro Porteño | - | Peñarol | 4 | - | - | 1:0 |
| 30/06/22 | Cerro Porteño | - | Palmeiras | 1 | - | - | 0:3 |
| 28/02/23 | Cerro Porteño | - | Curicó Unido | 4 | - | - | 1:0 |
| 04/05/23 | Cerro Porteño | - | Bolívar | 3 | - | - | 0:4 |
| 11/04/24 | Cerro Porteño | - | Alianza Lima | 4 | - | - | 1:0 |
| 30/05/24 | Cerro Porteño | - | Colo-Colo | 2 | - | 1 | 1:1 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 18/08/16 | Cerro Porteño | - | Fénix | 2 | - | 1 | 2:0 |
Colombia