| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 3 | 2 | - | 1 | 7 | - | - |
| away | 5 | 1 | 1 | 3 | 17 | - | - |
| overall | 8 | 3 | 1 | 4 | 24 | - | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | 1 | - | - | - | - | - |
| away | 2 | 1 | - | 1 | 8 | - | 2 |
| overall | 3 | 2 | - | 1 | 8 | - | 2 |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 17/04/08 | San Lorenzo | - | Caracas FC | 2 | - | - | 3:0 |
| 07/08/14 | Club Nacional | - | San Lorenzo | - | - | - | 1:1 |
| 19/03/15 | São Paulo FC | - | San Lorenzo | 5 | - | - | 1:0 |
| 13/04/16 | Deportivo Toluca | - | San Lorenzo | 6 | - | - | 2:1 |
| 04/05/17 | Athletico Paranaense | - | San Lorenzo | 3 | - | - | 0:3 |
| 14/09/17 | San Lorenzo | - | Lanús | 4 | - | - | 2:0 |
| 01/08/19 | Cerro Porteño | - | San Lorenzo | 3 | - | - | 2:1 |
| 07/04/21 | San Lorenzo | - | Santos FC | 1 | - | - | 1:3 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 21/10/09 | River Plate | - | San Lorenzo | 4 | - | 1 | 0:1 |
| 26/09/18 | Nacional | - | San Lorenzo | 4 | - | 1 | 2:0 |
| 04/08/23 | San Lorenzo | - | São Paulo FC | - | - | - | 1:0 |
Colombia