| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 4 | 3 | 1 | - | 9 | - | - |
| away | 4 | - | - | 4 | 7 | 1 | 1 |
| overall | 8 | 3 | 1 | 4 | 16 | 1 | 1 |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | - | - | 1 | 1 | - | 2 |
| away | 2 | - | - | 2 | 7 | - | 1 |
| overall | 3 | - | - | 3 | 8 | - | 3 |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 31/01/13 | Bolívar | - | São Paulo FC | 2 | - | - | 4:3 |
| 07/03/13 | São Paulo FC | - | Arsenal de Sarandí | 4 | - | - | 1:1 |
| 19/03/15 | São Paulo FC | - | San Lorenzo | 1 | - | - | 1:0 |
| 12/05/16 | São Paulo FC | - | Atlético Mineiro | 3 | - | - | 1:0 |
| 07/02/19 | Talleres de Córdoba | - | São Paulo FC | 2 | 1 | - | 2:0 |
| 23/09/20 | LDU Quito | - | São Paulo FC | 1 | - | - | 4:2 |
| 26/05/21 | São Paulo FC | - | Sporting Cristal | 1 | - | - | 3:0 |
| 18/08/21 | Palmeiras | - | São Paulo FC | 2 | - | 1 | 3:0 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 27/10/11 | Libertad | - | São Paulo FC | 3 | - | 1 | 2:0 |
| 01/10/22 | São Paulo FC | - | Independiente del Valle | 1 | - | 2 | 0:2 |
| 04/08/23 | San Lorenzo | - | São Paulo FC | 4 | - | - | 1:0 |
Colombia