| Copa Libertadores | Matches | W | D | L |  |
 |
 |
| home | 2 | 1 | - | 1 | 6 | 1 | - |
| away | - | - | - | - | - | - | - |
| overall | 2 | 1 | - | 1 | 6 | 1 | - |
| Copa Sudamericana | Matches | W | D | L | |
|
|
| home | 1 | 1 | - | - | 3 | - | - |
| away | 1 | - | 1 | - | 3 | - | - |
| overall | 2 | 1 | 1 | - | 6 | - | - |
| Copa Libertadores | Home | - | Guest | |
|
|
Results |
| 16/03/17 | Independiente Medellín | - | River Plate | 3 | - | - | 1:3 |
| 16/03/23 | Independiente Medellín | - | CD Magallanes | 3 | 1 | - | 2:0 |
| Copa Sudamericana | Home | - | Guest | |
|
|
Results |
| 26/04/24 | Independiente Medellín | - | Defensa y Justicia | 3 | - | - | 2:1 |
| 19/09/24 | Lanús | - | Independiente Medellín | 3 | - | - | 0:0 |
Brazil