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| 1st(1st leg) | KF Elbasani | - | KF Apolonia Fier | 0:0 | ||
| 2nd (2nd leg) | KF Apolonia Fier | - | KF Elbasani | 1:0 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KF Apolonia Fier | ||||
| 1st(1st leg) | Butrinti Sarandë | - | KS Shkumbini | 2:0 | ||
| 2nd (2nd leg) | KS Shkumbini | - | Butrinti Sarandë | 3:0 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KS Shkumbini | ||||
| 1st(1st leg) | Dinamo Tiranë | - | KS Kamza | 0:1 | ||
| 2nd (2nd leg) | KS Kamza | - | Dinamo Tiranë | 1:0 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KS Kamza | ||||
| 1st(1st leg) | KF Himara | - | KS Kastrioti | 0:2 | ||
| 2nd (2nd leg) | KS Kastrioti | - | KF Himara | 2:1 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KS Kastrioti | ||||
| 1st(1st leg) | KF Tërbuni Pukë | - | KF Bylis Ballsh | 0:2 | ||
| 2nd (2nd leg) | KF Bylis Ballsh | - | KF Tërbuni Pukë | 1:0 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KF Bylis Ballsh | ||||
| 1st(1st leg) | Olimpiku Tiranë | - | KF Skënderbeu | 2:2 | ||
| 2nd (2nd leg) | KF Skënderbeu | - | Olimpiku Tiranë | 7:2 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KF Skënderbeu | ||||
| 1st(1st leg) | KF Adriatiku Mamurrasi | - | KF Laçi | 0:3 | ||
| 2nd (2nd leg) | KF Laçi | - | KF Adriatiku Mamurrasi | 0:0 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KF Laçi | ||||
| 1st(1st leg) | KF Lushnja | - | KS Pogradeci | 5:0 | ||
| 2nd (2nd leg) | KS Pogradeci | - | KF Lushnja | 0:2 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KF Lushnja | ||||
| 1st(1st leg) | KF Ada Velipojë | - | FK Tomori Berat | 2:1 | ||
| 2nd (2nd leg) | FK Tomori Berat | - | KF Ada Velipojë | 1:0 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: FK Tomori Berat | ||||
| 1st(1st leg) | KS Iliria | - | FK Vllaznia | 0:2 | ||
| 2nd (2nd leg) | FK Vllaznia | - | KS Iliria | 2:1 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: FK Vllaznia | ||||
| 1st(1st leg) | KF Gramshi | - | Luftëtari Gjirokastër | 1:0 | ||
| 2nd (2nd leg) | Luftëtari Gjirokastër | - | KF Gramshi | 5:0 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: Luftëtari Gjirokastër | ||||
| 1st(1st leg) | KS Besëlidhja Lezhë | - | FK Kukësi | 2:4 | ||
| 2nd (2nd leg) | FK Kukësi | - | KS Besëlidhja Lezhë | 1:2 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: FK Kukësi | ||||
| 1st(1st leg) | KS Burreli | - | KS Besa | 1:4 | ||
| 2nd (2nd leg) | KS Besa | - | KS Burreli | 6:1 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KS Besa | ||||
| 1st(1st leg) | KS Gramozi | - | KF Teuta Durrës | 0:4 | ||
| 2nd (2nd leg) | KF Teuta Durrës | - | KS Gramozi | 3:0 dec. | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KF Teuta Durrës | ||||
| 1st(1st leg) | KF Naftëtari Kuçovë | - | Flamurtari Vlorë | 0:1 | ||
| 2nd (2nd leg) | Flamurtari Vlorë | - | KF Naftëtari Kuçovë | 4:1 | ||
| 1st(1st leg): 26/09/2012 15:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: Flamurtari Vlorë | ||||
| 1st(1st leg) | FK Partizani | - | KF Tiranë | 1:2 | ||
| 2nd (2nd leg) | KF Tiranë | - | FK Partizani | 1:0 | ||
| 1st(1st leg): 26/09/2012 18:00 | 2nd (2nd leg): 03/10/2012 13:30 | Winner: KF Tiranë | ||||
