 |
 |
|
|
| 1st(1st leg) | Fortaleza FC | - | Unión Magdalena | 2:1 (2:0) | ||
| 2nd (2nd leg) | Unión Magdalena | - | Fortaleza FC | 4:2 (3:0) | ||
| 1st(1st leg): 15/03/2023 20:15 | 2nd (2nd leg): 31/03/2023 01:30 | Winner: Unión Magdalena | ||||
| 1st(1st leg) | Tigres FC | - | Envigado FC | 1:1 (1:1) | ||
| 2nd (2nd leg) | Envigado FC | - | Tigres FC | 1:4 (0:0, 0:0) pso | ||
| 1st(1st leg): 15/03/2023 20:15 | 2nd (2nd leg): 29/03/2023 21:00 | Winner: Tigres FC | ||||
| 1st(1st leg) | Cortuluá | - | Real Cartagena | 1:3 (0:1) | ||
| 2nd (2nd leg) | Real Cartagena | - | Cortuluá | 2:1 (0:1) | ||
| 1st(1st leg): 15/03/2023 21:00 | 2nd (2nd leg): 30/03/2023 01:00 | Winner: Real Cartagena | ||||
| 1st(1st leg) | Llaneros FC | - | Jaguares de Córdoba | 1:1 (0:1) | ||
| 2nd (2nd leg) | Jaguares de Córdoba | - | Llaneros FC | 1:0 (1:0) | ||
| 1st(1st leg): 15/03/2023 23:00 | 2nd (2nd leg): 30/03/2023 22:00 | Winner: Jaguares de Córdoba | ||||
| 1st(1st leg) | Leones FC | - | Deportivo Cali | 0:0 (0:0) | ||
| 2nd (2nd leg) | Deportivo Cali | - | Leones FC | 2:0 (1:0) | ||
| 1st(1st leg): 16/03/2023 01:05 | 2nd (2nd leg): 29/03/2023 23:30 | Winner: Deportivo Cali | ||||
| 1st(1st leg) | Patriotas FC | - | Orsomarso SC | 0:0 (0:0) | ||
| 2nd (2nd leg) | Orsomarso SC | - | Patriotas FC | 1:0 (0:0) | ||
| 1st(1st leg): 16/03/2023 20:30 | 2nd (2nd leg): 28/03/2023 21:30 | Winner: Orsomarso SC | ||||
| 1st(1st leg) | Bogotá FC | - | Alianza Petrolera | 2:2 (1:2) | ||
| 2nd (2nd leg) | Alianza Petrolera | - | Bogotá FC | 1:0 (1:0) | ||
| 1st(1st leg): 16/03/2023 23:00 | 2nd (2nd leg): 29/03/2023 22:00 | Winner: Alianza Petrolera | ||||
| 1st(1st leg) | Deportes Quindío | - | Cúcuta Deportivo | 0:2 (0:0) | ||
| 2nd (2nd leg) | Cúcuta Deportivo | - | Deportes Quindío | 0:0 (0:0) | ||
| 1st(1st leg): 17/03/2023 01:05 | 2nd (2nd leg): 30/03/2023 21:30 | Winner: Cúcuta Deportivo | ||||
