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| 1st(1st leg) | Atlético Huila | - | Atlético Nacional | 0:0 (0:0) | ||
| 2nd (2nd leg) | Atlético Nacional | - | Atlético Huila | 4:2 (0:0, 0:0) pso | ||
| 1st(1st leg): 30/05/2018 01:45 | 2nd (2nd leg): 03/06/2018 00:00 | Winner: Atlético Nacional | ||||
| 1st(1st leg) | Deportes Tolima | - | Independiente Medellín | 1:0 (0:0) | ||
| 2nd (2nd leg) | Independiente Medellín | - | Deportes Tolima | 3:5 (0:0, 1:0) pso | ||
| 1st(1st leg): 31/05/2018 01:30 | 2nd (2nd leg): 03/06/2018 23:30 | Winner: Deportes Tolima | ||||
