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| 1st(1st leg) | Universidad SC | - | Deportivo Heredia | 2:1 (1:0) | ||
| 2nd (2nd leg) | Deportivo Heredia | - | Universidad SC | 2:0 (1:0) | ||
| 1st(1st leg): 05/06/2013 22:05 | 2nd (2nd leg): 08/06/2013 19:00 | Winner: Deportivo Heredia | ||||
| 1st(1st leg) | Xelaju MC | - | CSD Comunicaciones | 1:2 (0:1) | ||
| 2nd (2nd leg) | CSD Comunicaciones | - | Xelaju MC | 2:1 (1:1) | ||
| 1st(1st leg): 06/06/2013 04:00 | 2nd (2nd leg): 09/06/2013 01:00 | Winner: CSD Comunicaciones | ||||
| 1st(1st leg) | Deportivo Marquense | - | Deportivo Malacateco | 2:0 (2:0) | ||
| 2nd (2nd leg) | Deportivo Malacateco | - | Deportivo Marquense | 3:3 (1:2) | ||
| 1st(1st leg): 06/06/2013 19:00 | 2nd (2nd leg): 09/06/2013 20:00 | Winner: Deportivo Marquense | ||||
| 1st(1st leg) | Halcones FC | - | Deportivo Suchitepéquez | 3:1 (0:1) | ||
| 2nd (2nd leg) | Deportivo Suchitepéquez | - | Halcones FC | 1:1 (0:0) | ||
| 1st(1st leg): 06/06/2013 22:15 | 2nd (2nd leg): 09/06/2013 18:00 | Winner: Halcones FC | ||||
