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| 1st(1st leg) | Deportivo Guastatoya | - | Antigua GFC | 1:0 (0:0) | ||
| 2nd (2nd leg) | Antigua GFC | - | Deportivo Guastatoya | 2:0 (0:0) | ||
| 1st(1st leg): 15/05/2019 21:30 | 2nd (2nd leg): 18/05/2019 22:00 | Winner: Antigua GFC | ||||
| 1st(1st leg) | Deportivo Malacateco | - | Cobán Imperial | 2:2 (1:0) | ||
| 2nd (2nd leg) | Cobán Imperial | - | Deportivo Malacateco | 0:1 (0:0) | ||
| 1st(1st leg): 16/05/2019 18:00 | 2nd (2nd leg): 20/05/2019 02:00 | Winner: Deportivo Malacateco | ||||
