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| 1st(1st leg) | Deportivo Guastatoya | - | Antigua GFC | 2:0 (0:0) | ||
| 2nd (2nd leg) | Antigua GFC | - | Deportivo Guastatoya | 0:0 (0:0) | ||
| 1st(1st leg): 29/11/2023 21:00 | 2nd (2nd leg): 03/12/2023 01:00 | Winner: Deportivo Guastatoya | ||||
| 1st(1st leg) | Deportivo Malacateco | - | Comunicaciones | 2:0 (0:0) | ||
| 2nd (2nd leg) | Comunicaciones | - | Deportivo Malacateco | 5:0 (3:0) | ||
| 1st(1st leg): 30/11/2023 01:00 | 2nd (2nd leg): 02/12/2023 22:00 | Winner: Comunicaciones | ||||
| 1st(1st leg) | Deportivo Zacapa | - | CSD Municipal | 1:0 (0:0) | ||
| 2nd (2nd leg) | CSD Municipal | - | Deportivo Zacapa | 1:2 (1:0) | ||
| 1st(1st leg): 30/11/2023 21:00 | 2nd (2nd leg): 03/12/2023 17:00 | Winner: Deportivo Zacapa | ||||
| 1st(1st leg) | Xelaju MC | - | Achuapa | 3:1 (3:0) | ||
| 2nd (2nd leg) | Achuapa | - | Xelaju MC | 1:3 (0:1) | ||
| 1st(1st leg): 01/12/2023 02:00 | 2nd (2nd leg): 03/12/2023 20:00 | Winner: Xelaju MC | ||||
