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| 17/05/2022 | 16:00 | FK Tauras Tauragė | - | Marijampolė City | 1:4 | |
| 18/05/2022 | 16:00 | DFK Dainava | - | FK Panevėžys | 0:2 | |
| 16:00 | Neptūnas Klaipėda | - | FK Žalgiris | 0:1 | ||
| 24/05/2022 | 16:00 | FK Granitas Vilnius | - | Kauno Žalgiris | 0:4 | |
| 17:45 | FK Ataka | - | FK Riteriai | 1:5 | ||
| 25/05/2022 | 12:00 | Baltijos Futbolo Akademija | - | FC Hegelmann | 0:6 | |
| 17:00 | FK Sūduva | - | FK Banga Gargždai | 2:0 | ||
| 17:00 | FK TransINVEST | - | FK Jonava | 1:2 |
