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| 1st(1st leg) | CF América | - | CF Monterrey | 1:4 (0:3) | ||
| 2nd (2nd leg) | CF Monterrey | - | CF América | 3:2 (1:1) | ||
| 1st(1st leg): 04/12/2020 23:00 | 2nd (2nd leg): 08/12/2020 03:00 | Winner: CF Monterrey | ||||
| 1st(1st leg) | Gallos Blancos | - | UANL Tigres | 0:2 (0:1) | ||
| 2nd (2nd leg) | UANL Tigres | - | Gallos Blancos | 2:0 (1:0) | ||
| 1st(1st leg): 05/12/2020 01:00 | 2nd (2nd leg): 08/12/2020 01:00 | Winner: UANL Tigres | ||||
