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| 1st(1st leg) | Deportivo Guadalajara | - | CF América | 2:2 (0:1) | ||
| 2nd (2nd leg) | CF América | - | Deportivo Guadalajara | 2:0 (1:0) | ||
| 1st(1st leg): 02/05/2025 02:00 | 2nd (2nd leg): 05/05/2025 00:00 | Winner: CF América | ||||
| 1st(1st leg) | CF Monterrey | - | CF Pachuca | 1:0 (1:0) | ||
| 2nd (2nd leg) | CF Pachuca | - | CF Monterrey | 4:1 (2:1) | ||
| 1st(1st leg): 03/05/2025 03:00 | 2nd (2nd leg): 06/05/2025 02:00 | Winner: CF Pachuca | ||||
