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| 1st(1st leg) | Leones Negros II | - | Cimarrones de Sonora II | 0:3 (0:1) | ||
| 2nd (2nd leg) | Cimarrones de Sonora II | - | Leones Negros II | 0:2 (0:0) | ||
| 1st(1st leg): 27/10/2022 17:00 | 2nd (2nd leg): 30/10/2022 21:30 | Winner: Cimarrones de Sonora II | ||||
| 1st(1st leg) | Lobos ULMX | - | CF Pachuca II | 1:4 (0:3) | ||
| 2nd (2nd leg) | CF Pachuca II | - | Lobos ULMX | 4:2 (2:0) | ||
| 1st(1st leg): 27/10/2022 23:00 | 2nd (2nd leg): 31/10/2022 18:00 | Winner: CF Pachuca II | ||||
