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| 1st(1st leg) | Deportivo Toluca | - | Pumas UNAM | 2:2 (2:1) | ||
| 2nd (2nd leg) | Pumas UNAM | - | Deportivo Toluca | 0:2 (0:1) | ||
| 1st(1st leg): 03/12/2003 | 2nd (2nd leg): 05/12/2003 23:00 | Winner: Deportivo Toluca | ||||
| 1st(1st leg) | Cruz Azul | - | UANL Tigres | 0:1 (0:1) | ||
| 2nd (2nd leg) | UANL Tigres | - | Cruz Azul | 1:2 (1:2) | ||
| 1st(1st leg): 03/12/2003 | 2nd (2nd leg): 06/12/2003 | Winner: Cruz Azul | ||||
| 1st(1st leg) | Atlante | - | Santos Laguna | 3:1 (1:1) | ||
| 2nd (2nd leg) | Santos Laguna | - | Atlante | 2:2 (1:1) | ||
| 1st(1st leg): 04/12/2003 | 2nd (2nd leg): 07/12/2003 | Winner: Atlante | ||||
| 1st(1st leg) | Club Necaxa | - | CF Pachuca | 1:3 (0:0) | ||
| 2nd (2nd leg) | CF Pachuca | - | Club Necaxa | 1:2 (0:2) | ||
| 1st(1st leg): 04/12/2003 | 2nd (2nd leg): 07/12/2003 | Winner: CF Pachuca | ||||
