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| 1st(1st leg) | Gallos Blancos (old) | - | Deportivo Guadalajara | 2:1 (1:0) | ||
| 2nd (2nd leg) | Deportivo Guadalajara | - | Gallos Blancos (old) | 0:0 (0:0) | ||
| 1st(1st leg): 19/11/2011 23:00 | 2nd (2nd leg): 27/11/2011 01:00 | Winner: Gallos Blancos (old) | ||||
| 1st(1st leg) | Monarcas Morelia | - | Cruz Azul | 2:1 (0:1) | ||
| 2nd (2nd leg) | Cruz Azul | - | Monarcas Morelia | 1:2 (1:2) | ||
| 1st(1st leg): 20/11/2011 01:00 | 2nd (2nd leg): 26/11/2011 23:00 | Winner: Monarcas Morelia | ||||
| 1st(1st leg) | Jaguares Chiapas | - | Santos Laguna | 2:2 (0:2) | ||
| 2nd (2nd leg) | Santos Laguna | - | Jaguares Chiapas | 2:1 (1:0) | ||
| 1st(1st leg): 20/11/2011 22:00 | 2nd (2nd leg): 27/11/2011 23:00 | Winner: Santos Laguna | ||||
| 1st(1st leg) | CF Pachuca | - | UANL Tigres | 0:1 (0:1) | ||
| 2nd (2nd leg) | UANL Tigres | - | CF Pachuca | 3:0 (3:0) | ||
| 1st(1st leg): 21/11/2011 00:00 | 2nd (2nd leg): 28/11/2011 01:00 | Winner: UANL Tigres | ||||
