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| 1st(1st leg) | UANL Tigres | - | Atlas Guadalajara | 0:1 (0:0) | ||
| 2nd (2nd leg) | Atlas Guadalajara | - | UANL Tigres | 3:3 (1:0) | ||
| 1st(1st leg): 15/05/2019 17:00 | 2nd (2nd leg): 18/05/2019 15:00 | Winner: Atlas Guadalajara | ||||
| 1st(1st leg) | CF Monterrey | - | Santos Laguna | 3:0 (2:0) | ||
| 2nd (2nd leg) | Santos Laguna | - | CF Monterrey | 0:0 (0:0) | ||
| 1st(1st leg): 16/05/2019 15:00 | 2nd (2nd leg): 19/05/2019 17:15 | Winner: CF Monterrey | ||||
