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| 1st(1st leg) | Monarcas Morelia | - | Club Tijuana | 3:1 (1:0) | ||
| 2nd (2nd leg) | Club Tijuana | - | Monarcas Morelia | 3:1 (3:0) | ||
| 1st(1st leg): 27/11/2019 15:00 | 2nd (2nd leg): 01/12/2019 05:00 | |||||
| 1st(1st leg) | CF América | - | Atlas Guadalajara | 2:1 (0:1) | ||
| 2nd (2nd leg) | Atlas Guadalajara | - | CF América | 1:0 (1:0) | ||
| 1st(1st leg): 27/11/2019 16:00 | 2nd (2nd leg): 30/11/2019 16:00 | Winner: Atlas Guadalajara | ||||
| 1st(1st leg) | Deportivo Guadalajara | - | CF Monterrey | 1:1 (1:0) | ||
| 2nd (2nd leg) | CF Monterrey | - | Deportivo Guadalajara | 1:0 (0:0) | ||
| 1st(1st leg): 27/11/2019 18:00 | 2nd (2nd leg): 30/11/2019 15:00 | Winner: CF Monterrey | ||||
| 1st(1st leg) | CD Veracruz | - | Santos Laguna | 1:1 (0:1) | ||
| 2nd (2nd leg) | Santos Laguna | - | CD Veracruz | 2:1 (1:1) | ||
| 1st(1st leg): 28/11/2019 22:00 | 2nd (2nd leg): 01/12/2019 17:00 | Winner: Santos Laguna | ||||
