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| 1st(1st leg) | FK Rabotnički | - | Napredok Kičevo | 4:1 (2:1) | ||
| 2nd (2nd leg) | Napredok Kičevo | - | FK Rabotnički | 0:3 (0:2) | ||
| 1st(1st leg): 19/10/2011 13:00 | 2nd (2nd leg): 16/11/2011 12:00 | Winner: FK Rabotnički | ||||
| 1st(1st leg) | FK Turnovo | - | FK Bregalnica Štip | 3:1 (0:1) | ||
| 2nd (2nd leg) | FK Bregalnica Štip | - | FK Turnovo | 0:0 (0:0) | ||
| 1st(1st leg): 19/10/2011 13:00 | 2nd (2nd leg): 09/11/2011 12:00 | Winner: FK Turnovo | ||||
| 1st(1st leg) | FK Renova | - | FK Teteks | 6:0 (2:0) | ||
| 2nd (2nd leg) | FK Teteks | - | FK Renova | 2:3 (1:2) | ||
| 1st(1st leg): 19/10/2011 13:00 | 2nd (2nd leg): 08/11/2011 12:00 | Winner: FK Renova | ||||
| 1st(1st leg) | Vardar Skopje | - | 11 Oktomvri | 2:0 (1:0) | ||
| 2nd (2nd leg) | 11 Oktomvri | - | Vardar Skopje | 2:1 (0:0) | ||
| 1st(1st leg): 19/10/2011 17:00 | 2nd (2nd leg): 09/11/2011 12:00 | Winner: Vardar Skopje | ||||
