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| 1st(1st leg) | FC Den Bosch | - | De Graafschap | 0:0 (0:0) | ||
| 2nd (2nd leg) | De Graafschap | - | FC Den Bosch | 1:1 (1:1) | ||
| 1st(1st leg): 10/05/2012 18:00 | 2nd (2nd leg): 13/05/2012 11:30 | Winner: FC Den Bosch | ||||
| 1st(1st leg) | Willem II | - | Sparta Rotterdam | 2:1 (2:1) | ||
| 2nd (2nd leg) | Sparta Rotterdam | - | Willem II | 1:1 (0:1) | ||
| 1st(1st leg): 10/05/2012 19:00 | 2nd (2nd leg): 13/05/2012 13:30 | Winner: Willem II | ||||
| 1st(1st leg) | Helmond Sport | - | FC Eindhoven | 1:0 (0:0) | ||
| 2nd (2nd leg) | FC Eindhoven | - | Helmond Sport | 0:2 (0:2) | ||
| 1st(1st leg): 10/05/2012 19:00 | 2nd (2nd leg): 13/05/2012 13:30 | Winner: Helmond Sport | ||||
| 1st(1st leg) | SC Cambuur | - | VVV-Venlo | 0:0 (0:0) | ||
| 2nd (2nd leg) | VVV-Venlo | - | SC Cambuur | 4:3 (2:1) | ||
| 1st(1st leg): 10/05/2012 20:00 | 2nd (2nd leg): 13/05/2012 15:30 | Winner: VVV-Venlo | ||||
