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| 30/10/2021 | 01:00 | Deportivo del Este | - | Alianza | 0:1 (0:0) | |
| 21:00 | UD Universitario | - | San Francisco FC | 0:1 (0:0) | ||
| 22:00 | Tauro FC | - | Árabe Unido | 1:1 (0:1) | ||
| 31/10/2021 | 00:00 | Atlético Chiriquí | - | Herrera FC | 0:0 (0:0) | |
| 21:00 | Sporting San Miguelito | - | Plaza Amador | 1:1 (1:1) | ||
| 22:00 | Independiente de La Chorrera | - | Veraguas Club Deportivo | 3:1 (1:1) |
| » Tables | Home | Away | First round | Second round |
| 1 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Tauro FC | 13 | 7 | 4 | 2 | 16:8 | 8 | 25 |
| 2 |
|
Alianza | 13 | 7 | 4 | 2 | 12:7 | 5 | 25 |
| 3 |
|
Plaza Amador | 13 | 4 | 6 | 3 | 14:8 | 6 | 18 |
| 4 |
|
Deportivo del Este | 13 | 3 | 8 | 2 | 13:10 | 3 | 17 |
| 5 |
|
Árabe Unido | 13 | 3 | 6 | 4 | 8:9 | -1 | 15 |
| 6 |
|
Sporting San Miguelito | 13 | 3 | 6 | 4 | 9:13 | -4 | 15 |
| 2 | |||||||||
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Independiente de La Chorrera | 13 | 6 | 3 | 4 | 17:14 | 3 | 21 |
| 2 |
|
Herrera FC | 13 | 3 | 8 | 2 | 15:13 | 2 | 17 |
| 3 |
|
Veraguas Club Deportivo | 13 | 4 | 3 | 6 | 10:15 | -5 | 15 |
| 4 |
|
San Francisco FC | 13 | 3 | 4 | 6 | 8:14 | -6 | 13 |
| 5 |
|
UD Universitario | 13 | 4 | 1 | 8 | 10:17 | -7 | 13 |
| 6 |
|
Atlético Chiriquí | 13 | 2 | 5 | 6 | 8:12 | -4 | 11 |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs |
