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| 26/09/2018 | 14:00 | FK Kolubara | - | Partizan | 1:2 (0:1) | |
| 15:00 | FK Inđija | - | FK Zemun | 0:2 (0:2) | ||
| 15:00 | FK Sinđelić Beograd | - | FK Voždovac | 1:0 (1:0) | ||
| 15:00 | Radnik Surdulica | - | Radnički Pirot | 5:0 (1:0) | ||
| 15:00 | Mladost Bački Jarak | - | FK Čukarički | 0:2 (0:0) | ||
| 15:00 | TSC Bačka Topola | - | FK Rad Beograd | 2:0 (1:0) | ||
| 15:00 | FK Javor | - | FK Novi Pazar | 3:0 (0:0) | ||
| 15:00 | Proleter Novi Sad | - | Mladost Lučani | 3:4 (0:1, 1:1) pso | ||
| 15:00 | LFK Mladost | - | Spartak Subotica | 0:2 (0:1) | ||
| 17:00 | Mačva Šabac | - | FK Radnički 1923 | 1:0 (0:0) | ||
| 17:00 | Sloboda Užice | - | Borac Čačak | 0:3 (0:0) | ||
| 17:00 | OFK Bačka | - | Budućnost Dobanovci | 3:4 (0:1, 1:1, 1:1) pso | ||
| 18:00 | Vojvodina | - | Teleoptik Zemun | 2:0 (0:0) | ||
| 18:00 | Radnički Niš | - | FK Bežanija | 4:1 (1:0) | ||
| 17/10/2018 | 14:00 | FK Napredak | - | FK Metalac | 2:0 (1:0) | |
| 17:00 | Dinamo Vranje | - | Crvena Zvezda | 0:2 (0:1) |
