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| 19/05/2022 | 17:00 | FK Čukarički | - | FK Napredak | 0:0 (0:0) | |
| 22/05/2022 | 17:30 | Crvena Zvezda | - | FK Voždovac | 3:1 (1:0) | |
| 17:30 | Partizan | - | Radnički Niš | 2:0 (1:0) | ||
| 17:30 | TSC Bačka Topola | - | Vojvodina | 0:2 (0:0) |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Crvena Zvezda | 37 | 32 | 4 | 1 | 95:19 | 76 | 100 |
| 2 |
|
Partizan | 37 | 31 | 5 | 1 | 85:13 | 72 | 98 |
| 3 |
|
FK Čukarički | 37 | 15 | 15 | 7 | 54:34 | 20 | 60 |
| 4 |
|
Radnički Niš | 37 | 12 | 15 | 10 | 40:39 | 1 | 51 |
| 5 |
|
FK Voždovac | 37 | 13 | 10 | 14 | 48:45 | 3 | 49 |
| 6 |
|
TSC Bačka Topola | 37 | 13 | 9 | 15 | 51:56 | -5 | 48 |
| 7 |
|
Vojvodina | 37 | 13 | 6 | 18 | 44:51 | -7 | 45 |
| 8 |
|
FK Napredak | 37 | 10 | 8 | 19 | 31:51 | -20 | 38 |
| Champions League Quali. | |
