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| 1st(1st leg) | FK Senica | - | MŠK Žilina | 1:2 (0:0) | ||
| 2nd (2nd leg) | MŠK Žilina | - | FK Senica | 4:2 (1:2, 1:2) pso | ||
| 1st(1st leg): 23/10/2012 15:30 | 2nd (2nd leg): 06/11/2012 16:30 | Winner: MŠK Žilina | ||||
| 1st(1st leg) | FK Dukla Banská Bystrica | - | Spartak Trnava | 2:1 (0:0) | ||
| 2nd (2nd leg) | Spartak Trnava | - | FK Dukla Banská Bystrica | 3:1 (2:0) | ||
| 1st(1st leg): 23/10/2012 16:00 | 2nd (2nd leg): 06/11/2012 16:00 | Winner: Spartak Trnava | ||||
| 1st(1st leg) | MFK Košice | - | Spartak Myjava | 2:0 (1:0) | ||
| 2nd (2nd leg) | Spartak Myjava | - | MFK Košice | 3:1 (2:1) | ||
| 1st(1st leg): 24/10/2012 15:00 | 2nd (2nd leg): 06/11/2012 12:30 | Winner: MFK Košice | ||||
| 1st(1st leg) | Slovan Bratislava | - | MFK Ružomberok | 2:0 (1:0) | ||
| 2nd (2nd leg) | MFK Ružomberok | - | Slovan Bratislava | 3:1 (1:1) | ||
| 1st(1st leg): 24/10/2012 17:00 | 2nd (2nd leg): 06/11/2012 15:30 | Winner: Slovan Bratislava | ||||
