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| 20/11/2021 | 09:00 | FK Qo’qon 1912 | - | FC AGMK | 2:2 (0:1) | |
| 09:00 | So’g’diyona PFK | - | FC Nasaf | 1:1 (0:0) | ||
| 11:15 | Bunyodkor PFK | - | Surkhon Termez FK | 3:1 (2:1) | ||
| 11:15 | Lokomotiv Tashkent | - | Pakhtakor Tashkent | 0:3 (0:1) | ||
| 21/11/2021 | 09:00 | Andijon PFK | - | Navbahor Namangan | 1:2 (0:0) | |
| 09:00 | FK Mash'al Mubarek | - | Qizilqum Zarafshon | 2:1 (0:1) | ||
| 11:15 | Metallurg Bekobod | - | FK Turon | 1:0 (1:0) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pakhtakor Tashkent | 25 | 19 | 3 | 3 | 49:15 | 34 | 60 |
| 2 |
|
FC AGMK | 25 | 13 | 8 | 4 | 34:24 | 10 | 47 |
| 3 |
|
FC Nasaf | 25 | 13 | 6 | 6 | 41:21 | 20 | 45 |
| 4 |
|
So’g’diyona PFK | 25 | 11 | 11 | 3 | 27:15 | 12 | 44 |
| 5 |
|
Bunyodkor PFK | 25 | 12 | 6 | 7 | 40:28 | 12 | 42 |
| 6 |
|
Navbahor Namangan | 25 | 10 | 9 | 6 | 21:16 | 5 | 39 |
| 7 |
|
Lokomotiv Tashkent | 25 | 10 | 6 | 9 | 34:31 | 3 | 36 |
| 8 |
|
FK Qo’qon 1912 | 25 | 8 | 9 | 8 | 34:34 | 0 | 33 |
| 9 |
|
Qizilqum Zarafshon | 25 | 7 | 10 | 8 | 25:26 | -1 | 31 |
| 10 |
|
FK Mash'al Mubarek | 25 | 5 | 8 | 12 | 21:34 | -13 | 23 |
| 11 |
|
Surkhon Termez FK | 25 | 6 | 4 | 15 | 16:43 | -27 | 22 |
| 12 |
|
Metallurg Bekobod | 25 | 7 | 1 | 17 | 19:34 | -15 | 22 |
| 13 |
|
Andijon PFK | 25 | 4 | 7 | 14 | 22:40 | -18 | 19 |
| 14 |
|
FK Turon | 25 | 2 | 8 | 15 | 15:37 | -22 | 14 |
| Champions League | |
| Champions League Quali. | |
| Playoffs | |
| Relegation |
