| Period | Manager | Country | born |
| 03/04/2025 - 31/12/2025 | Ignacio Ithurralde |
|
30/05/1983 |
| 28/03/2025 - 02/04/2025 | Gerardo Miranda |
|
30/08/1963 |
| 08/07/2024 - 27/03/2025 | Álvaro Navarro |
|
28/01/1985 |
| 01/01/2024 - 07/07/2024 | Martín Varini |
|
02/08/1991 |
| 07/03/2022 - 07/12/2023 | Marcelo Méndez |
|
10/01/1981 |
| 01/03/2022 - 06/03/2022 | Gerardo Miranda |
|
30/08/1963 |
| 07/11/2021 - 28/02/2022 | Héctor Rodríguez Peña |
|
22/10/1968 |
| 23/07/2021 - 06/11/2021 | Leonel Rocco |
|
18/09/1966 |
| 14/03/2021 - 31/12/2021 | Eduardo Acevedo |
|
25/09/1959 |
| 15/11/2020 - 13/03/2021 | Gregorio Pérez |
|
16/01/1948 |
| 01/01/2020 - 12/11/2020 | Alejandro Orfila |
|
18/05/1976 |
| 01/04/2019 - 12/12/2019 | Ignacio Risso |
|
08/10/1977 |
| 01/01/2019 - 01/04/2019 | Jorge Da Silva |
|
11/12/1961 |
| 18/02/2016 - 31/12/2018 | Eduardo Acevedo |
|
25/09/1959 |
| 01/07/2015 - 17/02/2016 | Juan Tejera |
|
23/02/1956 |
| 01/01/2015 - 30/06/2015 | Mauricio Larriera |
|
26/08/1970 |
| 15/11/2014 - 31/12/2014 | Heber Cantera |
|
12/06/1956 |
| 01/01/2014 - 31/12/2014 | Fernando Curutchet |
|
06/10/1960 |
| 01/07/2012 - 31/12/2013 | Tabaré Silva |
|
30/08/1974 |
| 01/01/2012 - 30/06/2012 | Gustavo Díaz |
|
07/11/1974 |
| 23/05/2010 - 09/12/2011 | Pablo Repetto |
|
14/03/1974 |
| 01/07/2009 - 30/06/2010 | Gustavo Ferrín |
|
01/05/1959 |
| 01/01/2007 - 30/06/2009 | Jorge Da Silva |
|
11/12/1961 |
| 01/01/2001 - 30/06/2001 | Manuel Keosseian |
|
17/08/1953 |
| 01/01/1996 - 31/12/1996 | Juan Ahuntchaín |
|
15/01/1952 |
| 01/01/1994 - 31/12/1994 | Juan Ahuntchaín |
|
15/01/1952 |
| 01/01/1992 - 31/12/1992 | Juan Ahuntchaín |
|
15/01/1952 |
| 01/01/1990 - 31/12/1990 | Raúl Moller |
|
09/10/1950 |
| 01/01/1983 - 31/12/1984 | Gregorio Pérez |
|
16/01/1948 |
| 01/01/1982 - 31/12/1982 | Baudilio Jáuregui |
|
09/07/1945 |
| 01/01/1980 - 31/05/1980 | José de León |
|
23/09/1923 |
| 01/01/1977 - 31/12/1977 | Mario Patrón |
|
|
| 01/01/1952 - 31/12/1956 | Hugo Bagnulo |
|
23/07/1915 |
![Defensor Sporting [Women]](https://s.hs-data.com/bilder/wappen/mini/39071.gif?fallback=png "Defensor Sporting [Women]"){kind=small}
![Defensor Sporting [U20]](https://s.hs-data.com/bilder/wappen/mini/10182.gif?fallback=png "Defensor Sporting [U20]"){kind=small}
![Defensor Sporting [U17]](https://s.hs-data.com/bilder/wappen/mini/31685.gif?fallback=png "Defensor Sporting [U17]"){kind=small}
![Defensor Sporting [U15]](https://s.hs-data.com/bilder/wappen/mini/31686.gif?fallback=png "Defensor Sporting [U15]"){kind=small}