| Cup Winners Cup | M. | W | D | L | goals | |||
| at home | 1 | 0 | 1 | 0 | 1 | : | 1 | |
| Away | 1 | 0 | 0 | 1 | 1 | : | 6 | |
| ∑ | 2 | 0 | 1 | 1 | 2 | : | 7 | |
| overall | M. | W | D | L | goals | |||
| at home | 1 | 0 | 1 | 0 | 1 | : | 1 | |
| Away | 1 | 0 | 0 | 1 | 1 | : | 6 | |
| Neutral Place | 0 | 0 | 0 | 0 | 0 | : | 0 | |
| ∑ | 2 | 0 | 1 | 1 | 2 | : | 7 | |
| Cup Winners Cup | |||||
| 1963/1964 | 1. Round | Manchester United | - | Willem II | 6:1 (3:1) |
| 1963/1964 | 1. Round | Willem II | - | Manchester United | 1:1 (1:1) |
|
For games that were decided on penalties the score after 120 minutes will be included in the ranking |
Netherlands 
![Willem II [Women]](https://s.hs-data.com/bilder/wappen/mini/13615.gif?fallback=png "Willem II [Women]"){kind=small}
![Willem II [U21]](https://s.hs-data.com/bilder/wappen/mini/34846.gif?fallback=png "Willem II [U21]"){kind=small}
![Willem II [U18]](https://s.hs-data.com/bilder/wappen/mini/34870.gif?fallback=png "Willem II [U18]"){kind=small}
![Willem II [Youth]](https://s.hs-data.com/bilder/wappen/mini/21370.gif?fallback=png "Willem II [Youth]"){kind=small}
![Willem II [Youth B]](https://s.hs-data.com/bilder/wappen/mini/24887.gif?fallback=png "Willem II [Youth B]"){kind=small}
