 |
| MLS | 03/07/2021 | Columbus Crew | - | New England Revolution | 2:2 | 20.407 |
| MLS | 18/07/2021 | Columbus Crew | - | New York City FC | 2:1 | 19.113 |
| MLS | 22/07/2021 | Columbus Crew | - | Nashville SC | 0:0 | 18.395 |
| MLS | 05/08/2021 | Columbus Crew | - | D.C. United | 2:4 | 18.398 |
| MLS | 08/08/2021 | Columbus Crew | - | Atlanta United FC | 2:3 | 20.094 |
| MLS | 21/08/2021 | Columbus Crew | - | Seattle Sounders | 1:2 | 19.401 |
| MLS | 27/08/2021 | Columbus Crew | - | FC Cincinnati | 3:2 | 19.949 |
| MLS | 15/09/2021 | Columbus Crew | - | New York RB | 2:1 | 17.358 |
| MLS | 26/09/2021 | Columbus Crew | - | CF Montréal | 2:1 | 19.423 |
| 30/09/2021 | Columbus Crew | - | Cruz Azul | 2:0 | ??? | |
| WCQ CONCACAF | 14/10/2021 | USA | - | Costa Rica | 2:1 | 20.165 |
| MLS | 16/10/2021 | Columbus Crew | - | Inter Miami CF | 4:0 | 19.338 |
| MLS | 23/10/2021 | Columbus Crew | - | New York RB | 1:2 | 17.891 |
| MLS | 28/10/2021 | Columbus Crew | - | Orlando City | 3:2 | 16.676 |
| MLS | 07/11/2021 | Columbus Crew | - | Chicago Fire | 2:0 | 19.351 |
USA