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| Primera | 31/01/2010 | Defensor Sporting | - | Danubio | 0:1 | ??? |
| Primera | 13/02/2010 | Defensor Sporting | - | Central Español | 3:4 | ??? |
| Primera | 27/02/2010 | Defensor Sporting | - | Rampla Juniors | 2:1 | ??? |
| Primera | 20/03/2010 | Defensor Sporting | - | Tacuarembó | 2:3 | ??? |
| Primera | 28/03/2010 | Defensor Sporting | - | Peñarol | 2:3 | ??? |
| Primera | 09/04/2010 | Defensor Sporting | - | CA Cerro | 1:0 | ??? |
| Primera | 17/04/2010 | Defensor Sporting | - | River Plate | 1:1 | ??? |
| Primera | 25/04/2010 | Defensor Sporting | - | Montevideo Wanderers | 2:0 | ??? |
| Primera | 29/08/2010 | Defensor Sporting | - | Liverpool | 3:0 | ??? |
| Primera | 19/09/2010 | Defensor Sporting | - | Montevideo Wanderers | 1:2 | ??? |
| Primera | 02/10/2010 | Defensor Sporting | - | Bella Vista | 1:2 | ??? |
| Primera | 06/10/2010 | Defensor Sporting | - | CA Cerro | 2:0 | ??? |
| Primera | 12/10/2010 | Defensor Sporting | - | El Tanque Sisley | 3:1 | ??? |
| Primera | 24/10/2010 | Defensor Sporting | - | Rampla Juniors | 4:1 | ??? |
| Primera | 31/10/2010 | Defensor Sporting | - | Fénix | 5:1 | ??? |
| Primera | 13/11/2010 | Defensor Sporting | - | Central Español | 1:1 | ??? |
Uruguay