 |
 |
| MLS | 18/04/2021 | Chicago Fire | - | New England Revolution | 2:2 | 8.102 |
| MLS | 08/05/2021 | Chicago Fire | - | Philadelphia Union | 0:2 | 6.457 |
| MLS | 22/05/2021 | Chicago Fire | - | Inter Miami CF | 1:0 | 10.844 |
| MLS | 29/05/2021 | Chicago Fire | - | CF Montréal | 0:1 | 6.680 |
| MLS | 24/06/2021 | Chicago Fire | - | FC Cincinnati | 0:1 | 5.926 |
| MLS | 27/06/2021 | Chicago Fire | - | Philadelphia Union | 3:3 | 7.308 |
| MLS | 04/07/2021 | Chicago Fire | - | Atlanta United FC | 3:0 | 14.898 |
| MLS | 08/07/2021 | Chicago Fire | - | Orlando City | 3:1 | 8.002 |
| MLS | 22/07/2021 | Chicago Fire | - | D.C. United | 2:2 | 8.306 |
| MLS | 25/07/2021 | Chicago Fire | - | Toronto FC | 1:2 | 12.288 |
| MLS | 05/08/2021 | Chicago Fire | - | New York City FC | 0:0 | 8.371 |
| MLS | 08/08/2021 | Chicago Fire | - | New York RB | 2:1 | 11.894 |
| MLS | 15/08/2021 | Chicago Fire | - | Columbus Crew | 1:0 | 13.005 |
| MLS | 23/09/2021 | Chicago Fire | - | New England Revolution | 2:3 | 7.052 |
| MLS | 26/09/2021 | Chicago Fire | - | Nashville SC | 0:0 | 15.915 |
| MLS | 24/10/2021 | Chicago Fire | - | Real Salt Lake | 1:0 | 31.308 |
USA